>>214636596
I think 28 Days Later in space would be about as close as I could describe it. Add some insane body horror/creature work (preferably practical effects only) and a few scenes of terrifyingly torturous deaths/transformations (e.g. something akin to the DS2's opening transformation scene when Isaac is getting released), and I think we'd be about there. I think the toughest part would be getting the writing right. DS2 had a great balance of visceral horror combined with ruthless violence. The fact that you must dismember your enemies (seemingly prolonging their misery and certainly not the humane way to kill humans) and then benefit from stomping the shit out of them afterward made DS2 really push the "fight" in "fight or flight." The sound design made that experience, too, from its weapon sounds, enemy sounds, and so on. Capturing all of that shit would be tough in a movie but not impossible.