BloodRayne. You play as a hot vampire chick slaying monsters, zombies, nazis, and everything in between. I don't like hack and slash in general, so judge it for yourself.

Darkwatch. An FPS this time. You play as a Van Helsing-type dude working for Darkwatch, an ancient vampire-hunting organization. The catch is that you've been bitten and now possess vampiric abilities that you use against the enemies you fight. It's fun.

Ravenloft: Strahd's Possession. Dark fantasy party-based dungeon crawler. Evil big dick vampire steals a sacred amulet from your lord and your party must get it back. You fight off demons, skeletons, werewolves, lesser vampires, and other demonic creatures throughout the quest. It's fun.

Castlevania, Ghosts n' Goblins, Blood, Heretic & Hexen, and Vampire: The Masquerade - Redemption & Bloodlines need no introduction.

Haven't played these, but I'm fairly sure they follow the theme: Legacy of Kain: Blood Omen, Clive Barker's Undying, Demon's Crest, Nosferatu: The Wrath of Malachi, Buffy the Vampire Slayer, and Realms of the Haunting.