I don't technically lawnbase, but I carve out a mountain and make my factory shit in there.
Things to do:
>set up basic Mekanism based power
>set up Mekanism x4 ore duplications
>set up Mek nuclear reactor and turbine
>set up AE2
I still don't know if it is worth it grinding traders for fortune enchant books to combine and apply to several diamond picks.