>>76473839
That depends, on a macro scale CICO is unimpeachable, but if you delve into the minutia of how the body actually works on a chemical level it gets really complicated and hormones play a much larger role than you might think. So that's where this "CICO is a lie" stuff comes from because it kinda is, CICO is an over-simplification of a much more complex system, but ultimately it still works 99.9% of the time.