>>281419120
As far as story is concerned, we did get a little bit of Nodoka's back story, but all I can do is speculate on it as its just the doctors asking her not to give up, which is ultimately what she asked of the spirit in the MoTW leading to the powerup.

Maybe watching my baby brother go through it, but Nodo's disease sounds like some bad case of Croup, but it would be pretty late for her, unless the damage was just that severe.