From Spencer's run during Hunted, I guess MJ got used to creepy bugs in a way.
If Peter runs into a bunch of spiders swarming around like during the JMS run, I wonder if she'll get used to it. Makes me think that Peter having to protect a bunch of spiders would be kinda cool like one of those video game puzzles where he has to build a web to lead them across a gap.
Oh and MJ being covered in spiders like a fantasy villainess would be hot.