with all the shot type talk I wanna put out there that this is the set I have found the most success with
combining moon with Y1's familiar placement not only shreds bosses and pyramids (even when they hide behind other enemies because the familiars go beyond them) but cheeses the hell out of a lot of patterns by making a clear line in front of you, letting you save all the bombs you stock up from the hyper to instantly delete every pattern that gives you trouble
focused shot can be whatever but R1's damage and familiar placement being tightly in front of you does a great job of keeping up both your offense and defense