Ones that come to mind
>Maniac Mansion, ELITE, and M.U.L.E. on NES
>Sid Meier's Pirates Gold, Starflight, Syndicate, Theme Park, LHX Attack Chopper, James Pond II- Code Name Robocod (which is kind of a given considering how much this POS has been ported to TONS of different platforms at this point), Worms, Cannon Fodder, and The Immortal on Genesis/Mega-Drive
>Sim City on SNES