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>The SLC24A5 in Ethiopia maintains a substantial frequency with Semitic and Cushitic speaking populations, compared with Omotic, Nilotic or Niger-Congo speaking groups. It is inferred that it may have arrived into the region via migration from the Levant, which is also supported by linguistic evidence. In the San people, it was acquired from interactions with Eastern African pastoralists. Meanwhile, in the case of East Asia and the Americas, a variation of the MFSD12 gene is responsible for lighter skin colour. The modern association between skin tone and latitude is thus a relatively recent development
>According to Crawford et al. (2017), most of the genetic variants associated with light and dark pigmentation appear to have originated more than 300,000 years ago. frican, South Asian and Australo-Melanesian populations also carry derived alleles for dark skin pigmentation that are not found in Europeans or East Asians. Huang et al. (2021) found the existence of "selective pressure on light pigmentation in the ancestral population of Europeans and East Asians", prior to the divergence of their ancestors. Skin pigmentation was also found to be affected by directional selection towards darker skin among Africans, as well as lighter skin among Eurasians. Crawford et al. (2017) found evidence for the emergence of alleles associated with lighter and darker pigmentation prior to the origin of modern humans at c. 300kya
>The predominance of lighter skin among East Asians can be traced back to the positive selection for the rs1800414-G allele thought to date back to the Late Palaeolithic period (c. 25–30 kya), following the northward migration of modern humans from South/Southeast Asia. This allele is distinct from that observed among West Eurasians