Slophoreus' story has always been a jumbled mess and Shitji can't write or understand philosophy to save his life. The only thing that I got from this patch is Lygus' motivations kinda reminds me of Ratio's hatred of the Genius Society which hasn't been touched on in 2 years now.
Lygus' points that Nous' existence limits the pursuit of knowledge is pretty much true in the context of the story since if anyone even members of the Genius Society chosen by Nous get shanked by Polkakek for learning anything they "aren't supposed to know". Isn't the pursuit of knowledge supposed to be pushing the boundries? And if this knowledge is so dangerous then why didn't Polka kill Chadwick for making that planet destroying death ray? or kill Dr. Primitive trying to return to monke people?