Just to put Karmelita into perspective, she has the 2nd highest HP of any non-God Tuner, non-final boss in the series with just 150 points shy of 1st place, Crust King Khann. She's actually tied with Nightmare King Grimm for 2nd place, but for NKG you have Fragile Strength and Karmelita also blocks your attacks.

>Seth: 1185 HP
>Grey Prince Zote: 1200 HP
>Grandmother Silk: 1204 HP
>Soul Tyrant: 1250 HP
>Hollow Knight: 1250 HP
>Failed Champion: 1260 HP
>Crawfather: 1300 HP
>First Sinner: 1300 HP
>Karmelita: 1500 HP
>Nightmare King Grimm: 1500 HP
>Pure Vessel: 1600 HP
>Khann: 1650 HP
>Radiance: 1700 HP
>Lost Lace: 1800 HP