>>150060750
Isaac should reasonably take most categories except for general intelligence since he’s going up against a Quantum Physicist.

Isaac is generally more resourceful, more experienced, and his arsenal is arguably way more dangerous than most weaponry in Half-Life. Part of that being due to the Necromorphs literally shapeshifting themselves into different forms and iterations. His kinesis module allows him to pick up anything on a whim so he could realistically just telekinetically throw Gordon’s more busted weapons away from him like the Tau Cannon, Gluon Gun, or the Super Gravity Gun. And considering the setting of Dead Space tends to be more dark, claustrophobic, where any dead or decaying organic matter like swarmers which are just pieces of literal skin and chunks of flesh can become hostile to stalkers that literally hide and do hit-and-run tactics, it gives Isaac far more preparation dealing with enemies that try to be smart and sneaky. He’s also got superhuman strength since he can literally rip off limbs and crush heads just by himself.