>>712508908I imagine a fair amount of the sidequests got trimmed down for time, to prioritize finishing the game. There's several threads that go unresolved (the lockbox given to you in an alley, who killed the scavengers in Eidos 7, etc), and they've directly mentioned that Mann had a larger role in the game originally but it had to be cut down during development, they did restore his boss fight in the new patch thankfully. But they might follow up on some of the cut material in a sequel.