>>716126450there's so much focus on Los Santos that everything outside of the city gets forgotten about. there's one mission in Paleto Bay, about three in Sandy Shores, and that's it.
beyond that, the entire eastern shore of the map is functionally inaccessible and not used for anything, and the mountains are so large that you can't actually do anything there because the steepness makes them too hard to climb.
there's also really not that much to do in the city outside of structured story missions.