>>717053741 (OP)
Prior to Etrian Odyssey 4, the games in the series are presented as bright, and colourful fantasy, but there isn't much in terms of high fantasy 'magical' content - your healers are medics, your Warmagus use drug concoctions, and your Alchemists utilize mechanical gauntlets that cast their spells. Paladins using a heal, and Hexers using curses (and manipulating kotodama) are outliers, but the majority of the other classes are pretty grounded. Come 4, though, they introduce weird stuff like Arcanists, and Runemasters, which are a lot harder to rationalize, and in 5, they add a straight up necromancer class that can spawn ghosts and shit.
The monsters are generally mutated wildlife, automatons, or the occasional animated statue, with undead creatures only becoming common place in 5. Like, there are ghosts in prior entries, but they're treated more like spooky mysteries of the labyrinth, that don't get much focus.
At the end of two, though, the final stratum of the main campaign is a giant space ship humanity used to leave the planet, because it had become inhospitable due to excess pollution. The final boss is a robotics-expert who uploaded his consciousness to a giant transforming mecha, and the 'grail of kings' you're seeking is actually a science mcguffin capable of genetic alteration. Except it's not his field of expertise, so he sucks at it, and all the bosses you fight in the labyrinth are actually genetic mutant failures, as he seeks to give humanity true eternal life. His heart is in the right place, and he even gives you the option to leave so he can continue his studies.
Fantasy turning having heavy science fiction is fun