>>717657034
Real world cyborgs (people with total artificial heart replacements, medication pumps, pace makers, silicone breasts, artificial joints, to name but a few) don't need to take immunosuppressive drugs.
Appliances are coated in chemically inert coatings that the body goes "must be a rock that got stuck in grugg, better not mess with it"
Organ transplants are different, human organs are orders of magnitude more complex than even the scifi augments (I guess except for the nanotech stuff in original DX), they operate through chemical exchange via cellular receptor sites, a metabolically active process, whereas today's cybernetic implants (not that we call them that obviously) are crude passive systems looking for gross macroscopic changes like voltage or muscle position or even external signals (someone or a computer pushing a button).
So no, you're wrong. If there were things sticking into the body from the outside (this is called "communicating"), that's problematic but even people with ports for cancer meds don't need to take immunosuppressives. Basically a full body augmech is going to be a robot with a chunk of human sitting inside it, with maybe limited internal wireless signal sending/receiving through the skin. That's how cochlear implants work, they have an external "ear" that sends signals to the internal device but it's done via a wireless signal and magnets (so the device can adhere to you without something sticky).