>>723121624 (OP)
No, because Miku is a non character it's impossible to come up with anything earnest for her that isnt rhythm or porn because she has no defining characteristics of any kind beyond being an anime girl who sings.
So I'll come up with an original premise. It's a story oriented game called "Miku becomes a person (wow!)". In the game, you play as Miku put into the real world, but much ot her chagrin, millions of braindead coomer faggots want to anally rape her and tickle her feet constantly. So you have to use your money to hire bodyguards and robots to fend off the tasteless fag hordes who love you for literally no reason whatsoever. If they manage to catch you, you lose. It's like an open world horror game where you are constantly being hunted by random NPCs. Thankfully, they are all fat, so it is not hard to get away. The game ends with Miku shaving her head, smoking 9 packs of cigarettes a day to ruin her voice, and becoming a fat lesbian dyke so retards will finally stop fawning over her and start liking better waifus and she can live a normal life. The end.