>>724149130
Consider what encounters you may face and prepare accordingly
It's ok to take cards just to deal with certain fights you are bad at, just don't overdo it. Slay the Spire's encounters test your deck in different ways and so it needs to be versitile to win. This means you need to find options for different scenarios.
The general rule for deckbuilding is drafting damage in early act 1 to beat the hallway fights and elites into getting defensive- and frontloaded options for act 2 and picking up scaling when throughout act 2, or even act 1 depending on how your run is going. Dont add more cards than you need since that dilutes your deck making it less likely for you to draw what you need when you need it
Potions use is really important and you should learn when to use them and how much hp each potion is roughly worth. Dont waste them but dont be afraid to use them if you would otherwise take a nasty hit either this turn or later. There is a lot more to be said about potions but since you are new I wont elaborate
Dont be afraid to upgrade instead of resting, especially on lower acensions. Upgrading cards can often save you similar amounts of hp to what you would gain by resting outright while providing you better scaling
Also try to play with your relics, keep track of them and set them up between fights, that will help you immensly
Lastly removes are good but saving money so you have at least 300+ gold for each shop is good, it does depend but as a new player you shouldnt go too to many shops since you'll lose out on relics and dont know how to take advantage of them
Also take more fights, new players always dodge combat when they shouldnt. Fights give gold, cards, potions and lets you stack certain effects and relics. They are usually better than events, especially in act 1
