>>724631042
The general idea is to skip every pack reward EGO gift for the entire run, since if you max out your starlight buffs you'll have every ego gift by floor 10 anyways.
Also, every status has combos of gifts that enable the status to stack and enable gifts for buffs/enemy debuffs. Every T4 status gift is useful except burn, though you also need the frog eye for the tremor one to be good.
If you stack every offense level buff/debuff you're increasing your own by like 30 and dropping enemies' by about the same so you can steamroll until about floor 14, though most of the effects don't apply turn 1 so turn 1 is often rough as hell. It's also really RNG since you want level up events and piece of relationship which can't be forced, and even in the extreme area there are the secret battle nodes which drop a +1 coin power gift each that's supremely RNG to encounter.
And I'm no expert on every extreme pack to take/avoid, but at least the Wild Hunt one should be avoided since the T3 wrath pettacula at the end will just fucking one shot your units with their counters.