The Pokémon franchise has a very wide target audience, for male and females, all ages. But still more of a focus on children, and did also start off more so on the male side, but still not totally one way. So just because the franchise has some pretty, cute, pink or girly stuff in it. Is nowhere near enough to make Pokémon as a whole be a female only franchise, it's just because it has a very general target audience, so there's variety to appeal to many different groups.
>>58188900
If the Pokémon franchise really had been for a female only target audience. Then for some of the drastic changes I'd say the franchise would have. One major thing being that It'd be highly likely that Pokémon Battles would just outright not exist, this one change alone would result in the anime being very different the games being a very different genre entirely. The games could maybe then be more like a pet sim series, or some game with you just go around meeting characters and doing stuff, It's kind of difficult to say for sure exactly what. If anything, Pokémon Contests or something like it may replace Pokémon Battles, but of course being different from the Pokémon Contests we have, being more in-depth but also likely lacking the five Categories from the games, so possibly more like what we know of as Pokémon Contests from the anime. There would be quite in-depth mechanics for interacting with and caring for Pokémon. Of course there would be player character customisation. And that would also of course likely mean dressing up Pokémon too.
>>58188905
This too. How male characters would have been handled is a whole topic of its own. For female only target audience franchises, there's quite a few different ways they handle male characters.