>>33302641 (OP)>truly give up on people, friends, and relationships?Bet everything on yourself instead.
Seek what is important to you, what brings you joy, what you find meaningful, etc. Then you will eventually find yourself having given up on people, friends, and relationships in favour of your own values you have developed.
People, friends, and relationships will only matter to you as much as they matter to your own pursuits, and as long as you don't give up on yourself, you will always find a way to make connections with people on your own terms in ways that suit your needs.
You will have to get used to having people come and go in your life, because hey, you are looking to give up on people, friends and relationships, are you not?
If you are going to go down this path, make sure to never give up on yourself or become your own worst enemy (especially by giving into your own human folly - greed, arrogance, hubris, ignorance, etc).
You will have to keep yourself accountable, and this has been the toughest part for me.
All the best to you.