>>16837353
>>16837357
BTW, i can show you my model study that i would perform to check if we deal with a planetary genocide of human species or not.
Design: Prospective, multicenter cohort study with 10k participants (5k vaccinated, 5k age/sex/comorbidity-matched unvaccinated controls), stratified by vaccine type/dose. Baseline and serial assessments at 6, 12, 24, 60 months post-vaccination.
Endpoints: Primary - genomic instability (de novo mutations, CNVs, LOH via WGS); secondary - transcriptomic dysregulation (scRNA-seq), epigenomic shifts (ATAC-seq, methylation arrays), proteomic alterations (mass spec) and clinical outcomes (cancer, autoimmunity via EHR linkage).
Technologies: High-throughput WGS (Illumina NovaSeq, 30x coverage) for variants, long-read sequencing (PacBio/Oxford Nanopore) for structural variants, CRISPR-Cas9 screens for spike protein-mRNA interactions, spatial omics (Visium) for tissue-specific effects, AI/ML (DeepVariant, AlphaFold) for causal modeling.
Analysis: Differential expression via DESeq2/GSEA, Mendelian randomization for causality, multi-omics integration (MOFA+). Power: 80% to detect 1% instability risk elevation (α=0.05).
Ethics: IRB-approved, informed consent, diverse recruitment.
Cost: circa $50 million; timeline: 10 years.
Validates/refutes long-term risks via unbiased, scalable genomics. Even small-scale variants taking much less time should be performed ASAP imo. Thats a real science, and science shouldnt be feared.