Search Results
6/21/2025, 7:25:39 PM
>>63873140
>Nobody is digging one of these surreptitiously.
...without figuring newer technologies like flame-jet drilling, such as Earthgrid is doing?
>>63873156
Deeply buried hardened targets. There is a whole body of military literature about them, and a lot of people point out how generally shitty existing "solutions" are.
>Nobody is digging one of these surreptitiously.
...without figuring newer technologies like flame-jet drilling, such as Earthgrid is doing?
>>63873156
Deeply buried hardened targets. There is a whole body of military literature about them, and a lot of people point out how generally shitty existing "solutions" are.
6/15/2025, 5:57:58 AM
>>76261909
>Yes but none of the stuff we know about pre-2070 or so will. Topical cyclosporine might but it also increases risk of skin cancer.
The cyclopo-boring literature some boomer shit by now. Ain't nobody tryin' to grow carcinomas and melanomas and melanias or whatever instead of hair. All the serious researchers are farther down the Wnt/β-Catenin signaling rabbit hole by now.
>Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles
>https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2003705
>Through microarray analysis we identified the Wnt inhibitor, secreted frizzled related protein 1 (SFRP1), as being down-regulated in the dermal papilla (DP) of CsA-treated human scalp hair follicles (HFs) ex vivo.
>inhibiting SFRP1 activity through the SFRP1 antagonist, WAY-316606, enhanced hair shaft production, hair shaft keratin expression, and inhibited spontaneous HF regression (catagen) ex vivo
>Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
>https://www.mdpi.com/1422-0067/21/14/4915
>Tocotrienol, 3,4,5-tri-O-caffeoylquinic acid, Loliolide, Sinapic acid, Costunolide, Baicalin, Silibinin, Ginkgo biloba extract, Morroniside, polygonum multiflorum extract, Prunus mira Koehne, Red ginseng oil (RGO), Aconitie ciliare tuber, Thuja orientalis, Malva verticilata
>Yes but none of the stuff we know about pre-2070 or so will. Topical cyclosporine might but it also increases risk of skin cancer.
The cyclopo-boring literature some boomer shit by now. Ain't nobody tryin' to grow carcinomas and melanomas and melanias or whatever instead of hair. All the serious researchers are farther down the Wnt/β-Catenin signaling rabbit hole by now.
>Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles
>https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2003705
>Through microarray analysis we identified the Wnt inhibitor, secreted frizzled related protein 1 (SFRP1), as being down-regulated in the dermal papilla (DP) of CsA-treated human scalp hair follicles (HFs) ex vivo.
>inhibiting SFRP1 activity through the SFRP1 antagonist, WAY-316606, enhanced hair shaft production, hair shaft keratin expression, and inhibited spontaneous HF regression (catagen) ex vivo
>Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
>https://www.mdpi.com/1422-0067/21/14/4915
>Tocotrienol, 3,4,5-tri-O-caffeoylquinic acid, Loliolide, Sinapic acid, Costunolide, Baicalin, Silibinin, Ginkgo biloba extract, Morroniside, polygonum multiflorum extract, Prunus mira Koehne, Red ginseng oil (RGO), Aconitie ciliare tuber, Thuja orientalis, Malva verticilata
Page 1