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1. Unpublished MRI Case Report – Kingston, Ontario
Study: Pre- and post-circumcision MRI imaging of a male infant.
Findings: Claimed persistent changes in limbic, frontal, and temporal brain regions following unanesthetized circumcision.
Status: Unpublished, allegedly suppressed; single-subject case.
Citation: Referenced in activist and grey literature.
Link: https://www.sami-aldeeb.com/study-circumcision-permanently-alters-the-brain-researchers-threatened/
2. Taddio et al. (1997)
Title: "Effect of neonatal circumcision on pain response during subsequent routine vaccination"
Journal: The Lancet, 349(9052), 599–603.
Findings: Circumcised infants showed heightened pain response months later, indicating altered pain processing.
Relevance: Suggests long-term neurobehavioral sensitization.
Link: https://doi.org/10.1016/S0140-6736(96)10316-0
3. Gunnar et al. (1981, 1984); Talbert et al. (1993)
Findings: Significant elevations in cortisol levels post-circumcision, even with anesthesia.
Relevance: Prolonged neonatal stress exposure is linked to changes in brain development (e.g., HPA axis).
Note: Canadian sites involved in multi-center hormonal stress research.
Link (representative summary): https://www.scirp.org/journal/paperinformation.aspx?paperid=55727
4. Boyle, G. J. (2015)
Title: "Neonatal circumcision trauma: neuropsychological consequences"
Journal: NeuroQuantology, 13(4), 518–525.
Findings: Reviews existing literature on circumcision-related trauma; hypothesizes long-term neural consequences.
Relevance: Not original research, but synthesizes known Canadian and global data.
Link: https://www.neuroquantology.com/index.php/journal/article/view/897