>No character creation or character sheet. You have to play as Phyre with Fabien stuck in your head, there is no alternative. You can only choose your gender and clan
>No guns, except when you use them with the telekinesis discipline
>No melee weapons
>No Malkavian, Nosferatu or Gangrel
>Two clans locked behind DLC (though the Chinese Room is now reviewing this due to backlash)
>No stats or skills, you can only progress through disciplines
>No special dialogue choices like persuasion, seduction or intimidation
>No inventory
>No humanity system
>No frenzy mechanic
>No hacking or lockpicking
>No quest log (at least at the moment)