>>723253832
The best piece of advice is that it's far better (for your resources, time, and attention) to proactively destroy all nests that enter your pollution cloud. You go to them, not the other way around. Take advantage of the power spikes new tech gives you: grenades, the car, defender capsules, flamethrower turrets, and the tank.

2.0 gave tanks equipment grids, which means you can trick them out with energy shields, personal laser defenses, and even exoskeletons. Two of each along with one assembler making shells for your main gun - you'll become a God of Death tearing through nests.

More tips:
>Once you have flamethrower towers up biters are no threat there. It's harder to use them offensively but can be done.
>Pipes are good enough to serve as walls in the early game, and cheaper / easier to make
>Placing pipes (or any other object) in a chunk makes biters less likely to expand there. Some pipes in a winding circle around your starting area makes it far less likely biters will expand aggressively
>Once you have red chips, you can make efficiency modules. Everyone underestimates how much pollution electric miners produce; put E. modules in them and your resource patches will be much safer
>Get a mod like Even Distribution to make it easier to quickly put lots of bullets in lots of turrets
>The real best piece of advice is that this is entertainment. If biters make it less >fun, you don't have to play with them

We will party like it's 1999.