>>106202738
You go single rank (2x 16/24GB) if you're prioritizing speed & latency.
There are tradeoffs with different memory configs; no single solution.

>>105717363
XMP/EXPO is the low-hanging fruit.
The next is Buildzoid's ez timings for Ryzen CPUs.
https://www.patreon.com/posts/low-effort-rank-77403831