Thread 106352675

Yesterday, you all doubted this. Today OpenAI announced a collaboration with Retro Biosciences, a "longevity biotech startup". A significant pivot towards longevity research using narrow AI.
> https://openai.com/index/accelerating-life-sciences-research-with-retro-biosciences/

As mentioned yesterday, the next big thing to invest in is age reversal research and technology. Specially now that the AI bubble is about to pop and it turns out LLMs can't fix all of our medical problems.
The very first company to successfully commercialize an age reversal therapy will be worth trillions overnight. Literally everyone benefits from it, everyone suffers from aging (duh!). That's 8+ billion potential clients and will keep growing as long as humans keep breeding.

Don't say nobody warned you. You don't want to miss out on becoming rich with the next big thing, do you?

Yamanaka factors mentioned. That one guy from /sci/ is about to have a schizo moment.

>>106352675 (OP)
my computer is dying when I open that shit did they use gpt5 to write the website?

>>106352675 (OP)
>age reversal
and then what, die from overpopulation? do you really think this won't be yet another thing that will lead to our extinction?

>>106352950
>overpopulation
No, you retard. It won't, and the rate of births is getting lower, not higher. This might just be what will save a couple countries from population collapse.

>>106352750
qrd?

>>106353147
There was a guy on /sci/ in the cellular reprogramming generals who was experimenting with a bunch of supplements that supposedly activated these Yamanaka factors.
He claimed it could regrow your foreskin and other body parts. He also schizoposted that the government didn't want others to know about his supplement stack.

>>106352675 (OP)
pivoting to selling snake oil to boomer liches? daring i say

>>106353324
Given the article above it is likely he is a schizo, but is it possible the supplement stuff is partly real? I'm trying to improve my diet so I'm interested lol

>>106352750
he didn't invent yamanaka factors lmao... its not some obscure thing
the scientist got a noble prize for it ffs

>>106353346
Whether the supplements actually activated Yamanaka factors is questionable. I don't think a kilogram of parsley, turmeric, and butter is going to reverse aging and make you regrow your foreskin.

It was a just common nutrients found in food, but in liposomal form.

>>106353615
I know but he does genuinely believe that his supplement stack was activating them

>>106353345
better than selling snake oil to businesses in the form of AI. at least we might get useful medical research from this

>>106352675 (OP)
>promise AGI within our lifetime
>

>>106353754
It was always a marketing term.

>>106353754
AGI has already been delivered. AI has replaced so many jobs already. AI is the future.

>>106352950
It will be for billionaires only.

>>106352675 (OP)
ethically we should probably murder anyone that uses that kind of service

>>106352675 (OP)
>oy vey goyim, did you think you would finally be allowed tos top working once you were dead?
>what if...
>WE GOT RID OF DEATH!!! SO YOU COULD SLAVE AWAY FOR ALL OF ETERNITY!!! GLORY TO THE NEW WORLD ORDER AHAHAHAHAHHHAHAHAHHAHHAHAH AAAAAAAHAHAHAHAHAHAA

>>106354287
only the top 1% of the top 1%

>>106352675 (OP)
Number 1 of longevity is not being a fat fuck so I'm not sure why amerifats would be interested

>>106352675 (OP)
When's it coming out and how expensive will it be? Though I don't much care for the latter since I'm gonna bootleg it myself.

>>106353147
>geneticist stemfag here
Yamanaka factors make specilized somatic cells into pluripotent stem cells. Thing is, there's a reason yamanaka factors stops working after a certain stage in embryonic development. All but 3 of the 4 yamanaka factors lead to cancer formations. Neat, but old cells will produce old stemcells and nothing much will be fixed, unless we can create a blank universal genome to replace our current ones this tech will go nowhere.

>>106354364
>>WE GOT RID OF DEATH!!! SO YOU COULD SLAVE AWAY FOR ALL OF ETERNITY!!!
What if you, like, just don't work? What if you just, do whatever you want?

>>106354364
>>WE GOT RID OF DEATH!!! SO YOU COULD SLAVE AWAY FOR ALL OF ETERNITY!!! GLORY TO THE NEW WORLD ORDER AHAHAHAHAHHHAHAHAHHAHHAHAH AAAAAAAHAHAHAHAHAHAA
Now that I think about it, if I can stay in 20-30s for centuries I wouldn't mind a chill deadend government job.

None of this shit will do anything significant for humans. You can't even beat lifelong caloric restriction in animal models. And that gives humans at most 10% extra lifespan.
Talking with absolute certainty about Yamanaka factors or telomeres giving you any siginificant lifespan extension like a total midwit, when none of this shit addresses things like unavoidable DNA damage and mitochondria shitting the bed. You still have no way of breaking down glucosepane. A single prion is a death sentence. Biology is simply too complex. But somehow Sam Altman will solve aging because he combines the buzzwords 'AI' and 'Yamanaka' and only needs a few hundred billion in funding

>>106356477
cope tranny, agi is here and this is the next step for human evolution

>>106356500
trannies are more likely to like ai and be optimistic about medical breakthroughs

>>106356537
Cope tranny, you might finally actually be a woman.

>>106356543
>everybody is a tranny
ok retard

>>106352675 (OP)
Thanks but I'm sticking with fucking dying

>>106356440
Same. My heart never quite worked right anyway so a second wind might let me experience the rat race properly.
Plus stocks appreciating over 50 more years than usual? I'm game. I'll stay on Mr. Bones Wild Ride.

>>106352968
>This might just be what will save a couple countries from population collapse.
you can always ask Indians politely.

>>106356620
This

>>106356823
pff. You can die anytime you want to. This is equivalent to "I'm not brushing my teeth because it's against the natural order.". So is shitting in a toilet.

>>106356698
I'm not even gonna bother with the rat race. I'm gonna pick the most calm and deadend field, and coast. A cog so insignificant, no one's gonna bother to look if serves it's function.

>>106357151
I think we'll probably unlock some form of eternal life within the next 5 years, rolled out very slowly to people like us. And we'll unlock more as we go. But did you ever see the Good Place? They raise a fair point. Eternity even in paradise is eventual hell for a multitude of reasons, like...
Boredom: Infinite time strips novelty; everything eventually repeats.

Value erosion: Without endings, moments lose urgency and meaning.

Identity fatigue: You’d reinvent yourself endlessly until the “you” dissolves.

Isolation drift: Over infinite spans, relationships fracture or fade.

Choice paralysis: Unlimited options paralyze action; nothing feels decisive.

Stagnation: Growth needs struggle, but paradise erases friction.

Memory overload: Infinite experience eventually dulls or requires forgetting. Undoing “eternity” anyway.

Isn't this system we're actually living in already perfectly efficient in the end?

>>106357271
>Boredom: Infinite time strips novelty; everything eventually repeats.
Find new shit to do.

>Value erosion: Without endings, moments lose urgency and meaning.
A moment is a moment. It has no inherent value other than what you decide to place upon it.

>Identity fatigue: You’d reinvent yourself endlessly until the “you” dissolves.
Again, you decide what to do, where and when.

>Isolation drift: Over infinite spans, relationships fracture or fade.
Because they don't fracture or fade now?

>Choice paralysis: Unlimited options paralyze action; nothing feels decisive.
This is plain out retarded, just make a choice, simple as. Unless we're talking about figuring out which Hitman 3 version to buy because they made is obtuse as they possibly could. A plethora of choices is always a good thing.

>Stagnation: Growth needs struggle, but paradise erases friction.
Stagnation is the basis of a society and therefore civilization. Stagnation is what ensures order.

>Memory overload: Infinite experience eventually dulls or requires forgetting. Undoing “eternity” anyway.
Memory has always been a faulty thing. Eventually memory becomes as mailable as fantasy. It's why people kept journals in the first place.

>Isn't this system we're actually living in already perfectly efficient in the end?
No.

>>106357477
You still can't think in infinite's.

>>106352675 (OP)
new scam unlocked. give me 500 billion dollars and you can live forever.

>>106356477
>none of this shit addresses things like unavoidable DNA damage and mitochondria shitting the bed
Some animals can live for centuries without developing cancer, that means it's biologically possible. Figuring that out is what biological research is for.
>You still have no way of breaking down glucosepane
Figuring that out is what biological research is for.
>A single prion is a death sentence
Figuring that out is what resear... You know what, prion disease in humans is caused by a SINGLE protein misfolding, we know what the exact cause of prions are. The only reason we still haven't cured it, is because the disease is so rare that nobody wants to fund the development of a treatment. It's already possible to do so with mRNA tech and/or gene therapy.
>Biology is simply too complex
>Hurr durr nature too hard me give up before even try me retard
Yeah, sooo complex. Designing and mass producing nanometer scale microprocessors is more complex than any biological system. It just so happens that microprocessors receive an absurd amount of funding for R&D that longevity research usually doesn't.
>b-but...
Cope. We'll figure this shit out and cure most aging diseases in 10 years.

>>106356620
>Anon is an actual NPC

>>106357271
>everything eventually repeats
After long enough you'll start forgetting about things, and then you can do it again.
You really think after 200 years that you'll still remember everything about a game from the 21st century?
Just go play Skyrim and Oblivion again after you forget what happens in most of the game.
Or... you can just find new hobbies and switch to a different one when it becomes boring.

>Without endings, moments lose urgency and meaning
This is so dumb. Anyone who says this about their own LIFE must be an NPC. Who the fuck wants to literally stop existing for eternity (that's what death is, it's permanent) just because "moments lose urgency and meaning"?
I'm convinced that anyone who wants to die of old age, doesn't understand what death actually is.
You'll stop existing, forever, there's no return. Just sit there for 10 minutes and think about it really hard, your brain will eventually understand how craptastic that is.

>Identity fatigue... Isolation drift... Choice paralysis... Stagnation... Memory overload...
I'm now realizing that this post was written by an AI. At least if you're going to argue against immortality, don't use an immortal machine to argue for you.

>>106357653
And why would that be necessary for longevity?

>>106352750
>>106353147
Yamanaka figured out how to partially reverse cell differentiation about 15 years ago. Never heard the term Yamanaka factor before though.

>>106357804
Forgetting ≠ novelty. Rewatching a movie you forgot isn’t the same as living something for the first time, your brain still knows it’s a rerun. Even if you magically forgot everything perfectly then what the fuck is the point anyways? It's just a longer version of this.

And, using AI ≠ AI writing the post. Gud efficiency.

>>106357858
>Rewatching a movie you forgot isn’t the same as living something for the first time
>your brain still knows it’s a rerun
That's because you haven't forgotten about it. You've just lost most details, but your brain starts remembering as you watch the movie again, that's why it doesn't feel novel.
>And, using AI ≠ AI writing the post. Gud efficiency.
Except when AI gives retarded rationalizations for why immortality is bad, that no actual non-NPC human would. You're asking an immortal AI why immortality is bad, that's like asking a billionaire why money is bad.

>>106357722
>Some animals can live for centuries without developing cancer
Aquatic and/or with very slow metabolisms.

Even the smaller long lived tortoises have heart rates in the twenties. The huge ones significantly lower.

>>106357653
Neither can you. Presenting infinity as something horrible doesn't automatically mean you understand it. "Oh but if we live forever we're gonna be bored." Respectfully, the fuck kind of reasoning is this? Everything dies eventually, whether it's 50 years from now or 500 or 5000 years from now is irrelevant. Besides, this doesn't eliminate sickness, disease or getting hit by a bus.

>>106357974
> this doesn't eliminate sickness, disease or getting hit by a bus.
Without backups, it's really hard to extend healthy life much longer. We need to aim for digital life, even if we can't uplift ourselves at least let our spiritual descendants escape the horrific nature of nature.

>>106357961
>Aquatic and/or with very slow metabolisms.
It's interesting how the retards who argue that we "don't know enough about biology" to develop age reversal, end up mentioning slow metabolisms on biologically immortal species as a gotcha. EVERY. SINGLE. TIME.
Either we know enough to understand that aging is all about metabolism and heart rate (and thus can develop a solution), or we don't know enough to understand how to develop age reversal. Pick only one.

If it was about heart rates then professional athletes with physiologic sinus bradycardia would live significantly longer than most people.

>>106358026
What if we're already in a simulation?

>>106358140
We obviously are, but it doesn't change too much

>>106358026
>We need to aim for digital life
Except that we can't digitize ourselves without dying. It's the same as cloning yourself, and then giving the clone all your memories. That's not you anymore, it's now somebody else with your memories.
Brain uploading is not a solution to immortality.