>>719158816
Thats some “the fireflies couldn’t actually make a cure” level cope
Narratively the prince’s choice is meaningless if you try to headcanon your way out of the trolley problem

>>718978902
According to the audio logs, they’d never found a case of true immunity before. Ellie was the first. And even Joel never doubts it would work

Even in the first game he never doubts it. He just tells them to find someone else instead of Ellie.