>>149880852
Unit: E was already a somewhat established concept in the Prime show. It was the agency Fowler worked for (think like Sector Seven). Additionally in Prime Fowler made reference to things that were from other Hasbro properties (he name drops MASK in one episode and in another he refers to his squad of fighter jets as 'skystrikers' which is a GI JOE thing), these little references were meant to lead into something bigger.
UNIT: E as a show was meant to be an Avengers style series that would have had Transformers cross over with a whole bunch of Hasbro properties. Including GI JOE, M.A.S.K., JEM, Micronauts and the short lived Inhumanoids series from the 1980s.
As mentioned, Prime already was laying the groundwork for this series, this is why in the final episode of Prime Ratchet declared he was staying on Earth but then immediately went to Cybertron in the Movie. Because he was meant to be part of the Unit:E show set on earth while Transformers next show was going to be set in space. This is also what the plan for Jack, Miko and Raf were going forward.
So what happened? Well as mentioned Prime went overbudget so the budget that was allocated for Unit: E went into Prime instead. It's probably unlikely Unit: E would have lasted anyway, the HUB became Discovery Kids, just over a year later and almost all of Hasbro's plans for the channel fell apart.
Now what's interesting is in 2011 Hasbro did a promotional comic for Unit: E for the New York Comic con. It's kind of bare bones but it gives out the basic premise for what Unit: E was planned to be (in the comic, Unit E operated out of a space station, but the show it would be set on Earth). So they were working on this concept for a few years before it got the axe.